Genomics charts a deadly bacterium’s leap from pigs to humans

Nature
Workers sprinkle disinfection powder on spoiled pork

Pork is sprinkled with disinfectant in Beijing in 2005, when a pig-borne disease made scores of people in China ill. Credit: China Photos/Getty

Microbiology

Genomics charts a deadly bacterium’s leap from pigs to humans

Samples collected over several decades help scientists to trace the path taken by Streptococcus suis.

A genomic analysis has narrowed down where and when a deadly bacterium jumped from pigs to humans: in Europe in the 1960s or 1970s.

The bacterium Streptococcus suis has long been known as a pig pathogen. But, since 1998, it has caused three large outbreaks in people in China, and a sharp increase in human infections globally, making it a serious public-health concern.

To trace the evolution of S. suis, Jinquan Li at Huazhong Agricultural University in Wuhan, China, Ye Feng at Zhejiang University in Hangzhou, China, and their colleagues analysed 1,634 S. suis genomes collected from pigs and humans across 14 countries over 36 years. The genomes fell into three distinct groups, one of which was found mostly in humans. This group included strains that caused severe disease in zebrafish, which the authors used as a model of human disease.

Some of those strains had been collected from pigs that showed no signs of illness, suggesting that asymptomatic animals might have acted as carriers, spreading the bacterium to people. The researchers traced the human group’s origins to Europe during the 1960s and 1970s, when the continent was exporting pigs worldwide.

Articles You May Like

NASA’s SPHEREx Maps Water Ice Deposits in Cygnus X, Offering Clues to Earth’s Water​
Jerax Season 1 OTT Release: Where to Watch This Kannada Fantasy Comedy Series​
Happy Raj Now Available For Streaming Online: What You Need to Know​
Bitcoin Trades Near $78,000 as ETF Inflows and Macro Optimism Support Stabilising Cryptocurrency Prices​
iQOO Neo 10 Gets New Alpine White, Asphalt Black Colour Options in India: Price, Specifications​

Leave a Reply

Your email address will not be published. Required fields are marked *